Influence of cell type on the efficacy of plasmonic photothermal therapy

In this study, we explore the influence of cell type on the efficacy of Plasmonic Photothermal Therapy. This therapy relies on the use of gold nanorods and laser irradiation to locally increase the temperature and eliminate harmful cells. By monitoring uptake and cytotoxicity of gold nanorods and cell death after irradiation, on both cancer and noncancerous cells, we identify different susceptibilities to PPTT for different tissues and cell types. This underlines the need for appropriate controls to comprehend PPTT and creating systematic protocols to produce more useful data which can be directly compared.